October 23, 2009
Can long term use of PPIs Increase Your Weight?
While proton pump inhibitors (PPIs) can do a lot of good for patients diagnosed with GERD, they are also getting a lot of negative press lately.
First, there were reports that PPIs and Plavix together may increase the risk of recurrent heart attacks. Then there was news about use of PPIs associated with an increased risk of hospital-acquired pneumonia. A study showed there may be a link between the use of PPIs and an increased risk of hip fractures. Another study suggested PPIs may induce reflux symptoms and become addictive.
Now, it seems, PPIs may also increase your risk of gaining weight.
A clinical research team from Japan studied body weight and BMI in patients receiving long-term PPI therapy. Their study will be published in the World Journal of Gastroenterology.
The subjects were 52 patients with GERD and 58 sex- and age-matched healthy controls. GERD patients were treated with PPI for an average [...]
Source: About Heartburn / GERD










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